RAFAEL
FERRAZ-BANNITZ
Postdoctoral Research Fellow at Joslin Diabetes Center - Harvard Medical School
Mary-Elizabeth Patti Lab
DR. FERRAZ-BANNITZ
I'm a research scientist working to understand and create ways to control metabolic diseases, especially obesity, diabetes and cardiovascular diseases.
I enjoy generating new ideas and devising feasible solutions to broadly relevant to human health.
I have expertise in metabolism of glucose and energetic regulation in connection with Type 2 Diabetes, Obesity, Cardiovascular Disease, Aging, Post-Bariatric Hypoglycemia and Molecular and Cellular Biology of Metabolism.
PROFESSIONAL HISTORY
My Qualifications
April 2022 - Present
POSTDOCTORAL, JOSLIN DIABETES CENTER - HMS
We seek to understand the genetic and epigenetic effects involved in paternal transgenerational transmission.
Study of genetic inheritance transmitted by the father to the embryo (blastocyst).
Discover the mechanisms associated with the emergence of Post-bariatric hypoglycemia (PBH).
Study of the DNA methylation pattern in individuals with type 1 and 2 diabetes.
June 2016 - June 2021
SCIENTIFIC RESEARCHER, FMRP-USP
Developed a dietary strategy in a clinical environment capable of decreasing fasting glucose levels, lipid profile and blood pressure.
Studied changes in gut microbiota
Analyzed human adipose tissue RNA-seq
Analyzed the clinical and molecular effects from individuals working during the day and at nightshift work.
Analyzed the gene expression of adipose tissue in women undergoing bariatric surgery
April 2013 - May 2015
SCIENTIFIC RESEARCHER, UNIFESP-EPM
Identification and characterization of a gene in C.elegans capable of controlling lifespan
Developed the RNAi method to study the metabolic pathways modulated by the IMPACT gene
EDUCATION
June 2016 - June 2021
PH.D IN MEDICINE, UNIVERSITY OF SÃO PAULO - RIBEIRÃO PRETO MEDICAL SCHOOL
Advisor: Dr. Maria Cristina Foss-Freitas
Doctorate at Internal Medicine Department at Ribeirão Preto Medical School:
Dietary protein restriction reverses metabolic dysfunction in patients with the metabolic syndrome
Circadian misalignment induced by chronic nightshift work impacting directly on human metabolism
Roux-en-Y gastric bypass surgery can modulate ER stress and inflammation on subcutaneous adipose tissue in non-diabetic patients with obesity.
March 2019 - June 2020
VISITING PH.D CANDIDATE, HARVARD MEDICAL SCHOOL - JOSLIN DIABETES CENTER
Advisor: Dr. Mary-Elizabeth Patti
Clinical Research developed at Joslin Clinical Research Center:
Differential metabolic profile in subjects with neuroglycopenia after gastric bypass surgery.
April 2013 - May 2015
MASTER´S IN MOLECULAR BIOLOGY, FEDERAL UNIVERSITY OF SÃO PAULO - UNIFESP
Advisor: Dr. Marcelo A. Mori
Master's degree developed at Department of Medical Physics and Molecular Biology at Sao Paulo Medical School -UNIFESP:
IMPACT is a GCN2 inhibitor that limits lifespan in Caenorhabditis elegans.
February 2009 - December 2012
BIOMEDICAL SCIENCES, FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO - UFTM
Advisor: Dr. Wendell Ferreira Meira
Graduated in Biomedical Sciences from the Federal University of Triângulo Mineiro with specialization in clinical palology.
PROFICIENCIES
LANGUAGES
Portuguese: native
English: full professional
Spanish: full professional
Italian: limited working
French limited working
FELLOWSHIP
Joslin Diabetes Center Postdoctoral Fellowship 2022-2023
PhD Research Fellowship ABROAD 2019-2020 FAPESP - Brazil
PhD Research Fellowship 2016-2021 FAPESP - Brazil
Master Research Fellowship 2013-2015 São Paulo Research Foundation (FAPESP) - Brazil
Santander Research Initiation Scholarships 2010-2012 - Brazil
SKILLS AND TECHNIQUES
MOLECULAR BIOLOGY TECHNIQUES
Smart-seq3
PANDORA-seq
Bulk RNA-seq
Epigenetics (DNA methylation)
Metabolomic
Proteomics
Cloning
CELL CULTURE
Human PBMC
Single embryos
Human and mouse adipocytes isolated from subcutaneous adipose tissue
Primary cell culture
HT-29 cells
STUDIES IN:
Human
Mouse (C57Bl/6)
C. elegans
CLINICAL TRIALS
Nutritional clinical trial
Circadian rhythm
Post-bariatric hypoglycemia (PBH)
AWARDS
BEST POSTER PRESENTED AT BETH ISRAEL DEACONESS MEDICAL CENTER
The Best Poster Presented at BIDMC Translational Research Hub - Boston · May 2022
JOSLIN POSTDOCTORAL FELLOWSHIP
Selected as a Joslin Diabetes Center Postdoctoral Fellowship for 2022-2023
THE BEST POSTER PRESENTATION AWARD
The Best Poster Presentation Award in International Diabetes Conference - London · Oct 2018
PUBLICATIONS
I am very grateful to all my mentors who dedicated themselves for making me a better professional.